Genetics of M. tuberculosis
In 1998, the genome of the H37Rv strain was published. The size of the genome is 4 million base pairs, and has 3959 genes, out of these 40% of genes have their function characterised and another 44% are postulated with possible functions. Six pseudo genes are present within the genome.
Genome contains 250 genes involved in fatty acid metabolism, with 39 of these involved in the polypeptide metabolism generating the waxy coat. Such vast numbers of conserved genes show the revolutionary importance of the waxy coating to pathogen survival. M. tuberculosis can grow on the lipid cholesterol as a sole source of carbon, as genes involved in the cholesterol use pathways that have been important during various stages of the infection with tuberculosis. 10% of the coding genes are taken up by the amino acids that encode acidic, glycine-rich proteins. These proteins have a conserved N-terminal motif, deletion of which leads to impaired growth in granulomas and macrophages.
· H37Rv strain
· 3595 genes and 4 million base pairs
· Nine noncoding sRNAs and Glycine rich proteins
· Two X-linked (NEMO, CYBB) genes discovered in TB patients
· Recombinant human IFN-? thought to be effective in treatment
· TOX gene as strongly associated with the development of early-onset Pulmonary TB
Delegates are personally responsible for their belongings at the venue. The Organizers will not be held responsible for any stolen or missing items belonging to Delegates, Speakers or Attendees; due to any reason whatsoever.
Registration fees do not include insurance of any kind.
Please note that any (or) all transportation and parking is the responsibility of the registrant.
Press permission must be obtained from Allied Academies Organizing Committee prior to the event. The press will not quote speakers or delegates unless they have obtained their approval in writing. Allied Academies Pte. Ltd. is an objective third-party nonprofit organization. This conference is not associated with any commercial meeting company.
Requesting an Invitation Letter
For security purposes, letter of invitation will be sent only to those individuals who had registered for the conference. Once your registration is complete, please contact firstname.lastname@example.org or email@example.com to request a personalized letter of invitation.
Regarding refunds, all bank charges will be for the registrants account.
This cancellation policy was last updated on April 04, 2015.
Cancellation, Postponement and Transfer of Registration
All cancellations or modifications of registration must be made in writing to firstname.lastname@example.org
If Allied Academies cancels this event for any reason, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies event which must occur within one year from the date of cancellation.
If Allied Academies postpones an event for any reason and you are unable or unwilling to attend on rescheduled dates, you will receive a credit for 100% of the registration fee paid. You may use this credit for another Allied Academies event which must occur within one year from the date of postponement.
Transfer of registration
All fully paid registrations are transferable to other persons from the same organization, if registered person is unable to attend the event. Transfers must be made by the registered person in writing to email@example.com . Details must be included the full name of replacement person, their title, contact phone number and email address. All other registration details will be assigned to the new person unless otherwise specified.
Registration can be transferred to one conference to another conference of Allied Acdemies if the person is unable to attend one of conferences.
However, Registration cannot be transferred if it is intimated within 14 days of respective conference.
The transferred registrations will not be eligible for Refund.
Keeping in view of increased security measures, we would like to request all the participants to apply for Visa as soon as possible.
Allied Academies will not directly contact embassies and consulates on behalf of visa applicants. All delegates or invitees should apply for Business Visa only.
Important note for failed visa applications: Visa issues cannot come under the consideration of cancellation policy of Allied Academies, including the inability to obtain a visa.
If the registrant is unable to attend, and is not in a position to transfer his/her participation to another person or event, then the following refund arrangements apply:
Keeping in view of advance payments towards Venue, Printing, Shipping, Hotels and other overheads, we had to keep Refund Policy is as following slabs-
Accommodation Cancellation Policy:
Accommodation Providers (Hotels) have their own cancellation policies, and they generally apply when cancellations are made less than 30 days prior to arrival. Please contact us as soon as possible, if you wish to cancel or amend your accommodation. Allied Academies will advise the cancellation policy of your accommodation provider, prior to cancelling or amending your booking, to ensure you are fully aware of any non-refundable deposits.