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TB co-infections

TB  co-infections Photo
TB and HIV co-infection is that where people have both, either latent or active TB disease and also HIV infection. A condition, where someone has both HIV and TB, each disease speeds up the progress of the other disease. In addition to HIV infection is speeding up the progress from latent TB infection to active TB disease, in accordance TB bacteria also enhance the progression of HIV infection. Than many other opportunistic infections, TB occurs earlier in the course of HIV infection. In co-infected individuals, the risk of death is also twice that of HIV infected individuals without TB, even when antiretroviral therapy and CD4 cell count are taken into account. The provision of anti TB drug therapy and HIV antiretroviral treatment at the same time involves a number of potential difficulties including: A high pill burden, Drug – drug interactions, Cumulative drug toxicities
TB and Diabetes co-infection: Poorly controlled diabetes can lead to numerous complications, including neuropathy, vascular disease, and increased susceptibility to infection. Diabetes may also lead to increased susceptibility to the disease via multiple mechanisms that are caused by M. tuberculosis. The mechanisms include those directly related to cellular insulinopenia and hyperglycaemia as well as indirectly effects on macrophages and lymphocyte function, leading to diminished strength to hold the organism.
There are even other co-infections with Tuberculosis such as malaria, Typhoid fever, Dengue, hepatitis. 






























































































































































































TB and Diabetes co-infection: Poorly controlled diabetes can lead to numerous complications, including neuropathy, vascular disease, and increased susceptibility to infection. Diabetes may also lead to increased susceptibility to the disease via multiple mechanisms that are caused by M. tuberculosis. The mechanisms include those directly related to cellular insulinopenia and hyperglycaemia as well as indirectly effects on macrophages and lymphocyte function, leading to diminished strength to hold the organism.
There are even other co-infections with Tuberculosis such as malaria, Typhoid fever, Dengue, hepatitis. 

  • The Immune Reconstitution Inflammatory Syndrome (IRIS)
  • Comparison of nevirapine and efavirenz for rifampicin co-administration
  • Rifabutin-based treatment regimens
  • Optimal time to start antiretroviral therapy in HIV-infected TB patients
  • Research into effectiveness of programmes and means of collaboration with HIV/AIDS programmes
  • Priority research in the area of TB treatment for people living with HIV, hepatitis, malaria

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